AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A nonsense substitution mutation in a gene does the following:
A
switches the codon to a stop codon before it should have thus shortening the length of the protein
B
changes one amino acid to different one
C
does not change the amino acid being added.
Explanation: 

Detailed explanation-1: -Nonsense: A nonsense variant is another type of substitution. Instead of causing a change in one amino acid, however, the altered DNA sequence results in a stop signal that prematurely signals the cell to stop building a protein.

Detailed explanation-2: -A genetic alteration that causes the premature termination of a protein. The altered protein may be partially or completely inactivated, resulting in a change or loss of protein function.

Detailed explanation-3: -Definition. A nonsense mutation occurs in DNA when a sequence change gives rise to a stop codon rather than a codon specifying an amino acid. The presence of the new stop codon results in the production of a shortened protein that is likely non-functional.

Detailed explanation-4: -As noted earlier, a nonsense mutation occurs when a codon for an amino acid is changed to a stop codon. This results in a truncated and usually nonfunctional protein. Such a defect may be suppressed, at least partially, by changing the anticodon sequence of a tRNA molecule so that it recognizes the stop codon instead.

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