AP BIOLOGY

Detailed explanation-1: -A gene variant is a permanent change in the DNA sequence that makes up a gene. This type of genetic change used to be known as a gene mutation, but because changes in DNA do not always cause disease, it is thought that gene variant is a more accurate term.

Detailed explanation-2: -Mutations are changes in the genetic sequence, and they are a main cause of diversity among organisms. These changes occur at many different levels, and they can have widely differing consequences.

Detailed explanation-3: -A mutation is a change in the DNA sequence of an organism. Mutations can result from errors in DNA replication during cell division, exposure to mutagens or a viral infection.

Detailed explanation-4: -Gene variants (also known as mutations) can have varying effects on health, depending on where they occur and whether they alter the function of essential proteins. Variant types include the following: Substitution. This type of variant replaces one DNA building block (nucleotide) with another.

Detailed explanation-5: -Frameshift mutations The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein. This alteration occurs during translation because ribosomes read the mRNA strand in terms of codons, or groups of three nucleotides.