AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How can sickle cell disease be diagnosed?
A
Karyotype
B
Blood test
C
Physical
D
X-Ray
Explanation: 

Detailed explanation-1: -In adults, a blood sample is drawn from a vein in the arm. In young children and babies, the blood sample is usually collected from a finger or heel. The sample is then sent to a laboratory, where it’s screened for the sickle cell form of hemoglobin.

Detailed explanation-2: -The best way to check for sickle cell trait or sickle cell disease is to look at the blood using a method called high-performance liquid chromatography (HPLC). This test identifies which type of hemoglobin is present. To confirm the results of HPLC, a genetic test may be done.

Detailed explanation-3: -A complete blood count (CBC) test can help the care team monitor your child’s sickle cell disease. This test can help the care team find out if treatments are working.

Detailed explanation-4: -Healthcare providers can diagnose sickle cell anemia before your baby is born. They do this by taking a sample of the biological mother’s amniotic fluid or tissue from the biological mother’s placenta. Then, they examine the samples for signs of the sickle hemoglobin gene that causes the condition.

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