AP BIOLOGY

Detailed explanation-1: -If the mutation results in a change of one aminoacid, it is a missense mutation, no matter if it was result of a frameshift or point mutation.

Detailed explanation-2: -(MIS-sens myoo-TAY-shun) A genetic alteration in which a single base pair substitution alters the genetic code in a way that produces an amino acid that is different from the usual amino acid at that position. Some missense variants (or mutations) will alter the function of the protein.

Detailed explanation-3: -Missense Mutation A missense mutation is a DNA change that results in different amino acids being encoded at a particular position in the resulting protein.

Detailed explanation-4: -Missense: A missense variant is a type of substitution in which the nucleotide change results in the replacement of one protein building block (amino acid) with another in the protein made from the gene. The amino acid change may alter the function of the protein.

Detailed explanation-5: -Missense mutations may retain function, depending on the chemistry of the new amino acid and its location in the protein. Nonsense mutations produce truncated and frequently nonfunctional proteins. A frameshift mutation results from an insertion or deletion of a number of nucleotides that is not a multiple of three.