AP BIOLOGY

Detailed explanation-1: -Insertion or deletion of one or more nucleotides during replication can also lead to another type of mutation known as a frameshift mutation. The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein.

Detailed explanation-2: -point mutation, change within a gene in which one base pair in the DNA sequence is altered. Point mutations are frequently the result of mistakes made during DNA replication, although modification of DNA, such as through exposure to X-rays or to ultraviolet radiation, also can induce point mutations.

Detailed explanation-3: -Substitution, as related to genomics, is a type of mutation in which one nucleotide is replaced by a different nucleotide. The term can also refer to the replacement of one amino acid in a protein with a different amino acid.

Detailed explanation-4: -Frameshift Mutation A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.