AP BIOLOGY

Detailed explanation-1: -Mutational effects can be beneficial, harmful, or neutral, depending on their context or location. Most non-neutral mutations are deleterious. In general, the more base pairs that are affected by a mutation, the larger the effect of the mutation, and the larger the mutation’s probability of being deleterious.

Detailed explanation-2: -Most mutations are not harmful, but some can be. A harmful mutation can result in a genetic disorder or even cancer. Another kind of mutation is a chromosomal mutation. Chromosomes, located in the cell nucleus, are tiny threadlike structures that carry genes.

Detailed explanation-3: -A mutation whose fixation is independent of natural selection is termed a neutral mutation. Therefore selective neutrality of a mutation can be defined by independence of its fixation from natural selection.