AP BIOLOGY

Detailed explanation-1: -A translocation occurs when a piece of one chromosome breaks off and attaches to another chromosome. This type of rearrangement is described as balanced if no genetic material is gained or lost in the cell. If there is a gain or loss of genetic material, the translocation is described as unbalanced .

Detailed explanation-2: -A genetic change in which a piece of one chromosome breaks off and attaches to another chromosome.

Detailed explanation-3: -A change in chromosome structure and content caused by translocation is a translocation mutation. Many genes may be transferred between chromosomes. Such translocation mutations can cause disorders of growth, development, and function of the body’s cells and systems.

Detailed explanation-4: -Chromosomal translocations are one of the most common types of genetic rearrangements and are molecular signatures for many types of cancers. They are considered as primary causes for cancers, especially lymphoma and leukemia.

Detailed explanation-5: -Translocations arise when an end of one chromosome break is mistakenly joined to an end from a different chromosome break. Since translocations can lead to developmental disease and cancer, it is important to understand the mechanisms leading these chromosome rearrangements.