AP BIOLOGY

Detailed explanation-1: -A deletion, as related to genomics, is a type of mutation that involves the loss of one or more nucleotides from a segment of DNA. A deletion can involve the loss of any number of nucleotides, from a single nucleotide to an entire piece of a chromosome.

Detailed explanation-2: -It is a type of frameshift mutation characterized by the loss of one or more nucleotides from the segment of DNA. Example of deletion mutation is DiGeorge syndrome. DiGeorge syndrome is a disorder caused due to the deletion of a small segment of chromosome 22.

Detailed explanation-3: -Chromosomal Deletions Deletions involve the loss of DNA sequences. Phenotypic effects of deletions depend on the size and location of deleted sequences on the genome. For instance, deletions that span a centromere result in an acentric chromosome that will most likely be lost during cell division.

Detailed explanation-4: -The term “deletion” simply means that a part of a chromosome is missing or “deleted.” A very small piece of a chromosome can contain many different genes. When genes are missing, there may be errors in the development of a baby since some of the “instructions” are missing.