AP BIOLOGY

Detailed explanation-1: -Some of the more common single-gene disorders include cystic fibrosis, hemochromatosis, Tay-Sachs, and sickle cell anemia. Even though these diseases are primarily caused by a single gene, several different mutations can result in the same disease but with varying degrees of severity and phenotype.

Detailed explanation-2: -Types of Mutations All mutations fall into two basic categories: Those that produce changes in a single gene are known as gene mutations. Those that produce changes in whole chromosomes are known as chromosomal mutations.

Detailed explanation-3: -Mutations that produce changes in whole chromosomes are known as chromosomal mutations. Gene mutations involving a change in one or a few nucleotides are known as point mutations because they occur at a single point in the DNA sequence. Point mutations include substitutions, insertions, and deletions.