AP BIOLOGY

Detailed explanation-1: -An inversion occurs when a chromosome breaks in two places; the resulting piece of DNA is reversed and re-inserted into the chromosome. Genetic material may or may not be lost as a result of the chromosome breaks.

Detailed explanation-2: -(in-VER-zhun) A chromosomal defect in which a segment of the chromosome breaks off and reattaches in the reverse direction.

Detailed explanation-3: -Chromosomal inversion is a type of a large-scale mutation. Mutation is a change in the nucleotide sequence of a gene or a chromosome. It is a large-scale type of mutation since it involves several nucleotides of a gene within a large chromosomal region. Chromosomal inversions are a rearrangement within the chromosome.

Detailed explanation-4: -Inversions can generate structural problems with meiosis, as with some pericentric inversions. Alternatively, a breakpoint can disrupt an open reading frame or alter gene expression. The consequences can be deleterious, as in some human genetic diseases [6], but in other cases could cause an adaptive mutation.

Detailed explanation-5: -An inversion occurs when a chromosome undergoes a two breaks within the chromosomal arm, and the segment between the two breaks inserts itself in the opposite direction in the same chromosome arm.