AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are deletions and how do they affect the bases?
A
A deletion is when a Random base is deleted from the DNA sequence. This can change the way the base sequence is read and have further knock on effects
B
A is when the whole DNA sequence is deleted
C
I deletion is when the Genes are deleted
D
All of the above
Explanation: 

Detailed explanation-1: -A deletion changes the DNA sequence by removing at least one nucleotide in a gene. Small deletions remove one or a few nucleotides within a gene, while larger deletions can remove an entire gene or several neighboring genes. The deleted DNA may alter the function of the affected protein or proteins.

Detailed explanation-2: -(deh-LEE-shun) A type of genetic change that involves the absence of a segment of DNA. It may be as small as a single base but can vary significantly in size.

Detailed explanation-3: -A deletion, as related to genomics, is a type of mutation that involves the loss of one or more nucleotides from a segment of DNA. A deletion can involve the loss of any number of nucleotides, from a single nucleotide to an entire piece of a chromosome.

Detailed explanation-4: -Deletions occur when there is homologous but unequal recombination between gene sequences. Similar sequences in the human genome can cross over during mitosis or meiosis, resulting in a shortened portion of the gene sequence.

Detailed explanation-5: -Because an insertion or deletion results in a frame-shift that changes the reading of subsequent codons and, therefore, alters the entire amino acid sequence that follows the mutation, insertions and deletions are usually more harmful than a substitution in which only a single amino acid is altered.

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