AP BIOLOGY

Detailed explanation-1: -The correct answer is: Substitution.

Detailed explanation-2: -Insertion An insertion, as related to genomics, is a type of mutation that involves the addition of one or more nucleotides into a segment of DNA. An insertion can involve the addition of any number of nucleotides, from a single nucleotide to an entire piece of a chromosome.

Detailed explanation-3: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.

Detailed explanation-4: -Types of Mutations There are three types of DNA Mutations: base substitutions, deletions and insertions.

Detailed explanation-5: -Mutations in the HBB gene cause sickle cell disease. The HBB gene provides instructions for making one part of hemoglobin. Hemoglobin consists of four protein subunits, typically, two subunits called alpha-globin and two subunits called beta-globin. The HBB gene provides instructions for making beta-globin.