AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which gene point mutation will be most likely to have a REALLY BAD effect on the function of a protein?
A
a base substitution
B
a base deletion near the start of the coding sequence
C
a base deletion near the end of the coding sequence, but not the stop codon
D
two of the above
Explanation: 

Detailed explanation-1: -So, the correct option is ‘A single base insertion near the start of the coding sequence’.

Detailed explanation-2: -Answer and Explanation: (e) Insertion of one nucleotide is most likely to drastically affect a protein’s sequence.

Detailed explanation-3: -Answer and Explanation: A frameshift mutation is one that will most likely cause a change in the protein’s structure and function.

Detailed explanation-4: -The type of mutation that is likely to have the greatest effect on a protein is B. Nonsense mutation. This is because a nonsense mutation creates a premature stop codon, leading to an incomplete formation of a protein, severely affecting protein structure and function.

There is 1 question to complete.