AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following mutations is most likely to create a nonfunctional protein in a eukaryotic organism.
A
a deletion of a nucleotide in an intron
B
a deletion of a nucleotide near the beginning of an exon
C
a deletion of one nucleotide in the last codon of the last exon
Explanation: 

Detailed explanation-1: -A frameshift mutation is more likely to result in a nonfunctional protein.

Detailed explanation-2: -What kind of mutation is more likely to result in a nonfunctional protein, a frameshift (resulting from an insertion or deletion) or a point mutation? Silent mutation.

Detailed explanation-3: -Sometimes, gene variants (also known as mutations) prevent one or more proteins from working properly. By changing a gene’s instructions for making a protein, a variant can cause a protein to malfunction or to not be produced at all.

Detailed explanation-4: -Which type of substitution mutation has the greatest chance of leading to a nonfunctional protein? Explain your answer. A nonsense mutation has the greatest chance of producing a fully nonfunctional protein because it prematurely stops translation, thereby truncating the protein.

There is 1 question to complete.