AP BIOLOGY

Detailed explanation-1: -Copy number variation? (CNV) is a type of mutation where large chunks of DNA are inserted, repeated or lost. These regions of DNA can be between 10, 000 and 5, 000, 000 bases long.

Detailed explanation-2: -There are three types of DNA Mutations: base substitutions, deletions and insertions.

Detailed explanation-3: -In fact, the G-T mutation is the single most common mutation in human DNA. This mutation occurs about once in every 10, 000 to 100, 000 base pairs, which does not sound like a lot, but you have to consider that the human genome contains 3 billion base pairs.

Detailed explanation-4: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.

Detailed explanation-5: -Large-scale mutations may be further classified as follows: (1) amplifications (or gene duplications), (2) deletions of large chromosomal regions, and (3) chromosomal inversions. Amplifications are mutations where there are multiple copies of chromosomal regions.