HEREDITY
NONDISJUNCTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The likely cause of genetic disorders is ____
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Nondisjunction
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Overfertilization
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Uncontrolled Meiosis
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Translocation
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Explanation:
Detailed explanation-1: -Nondisjunction means that a pair of homologous chromosomes has failed to separate or segregate at anaphase so that both chromosomes of the pair pass to the same daughter cell.
Detailed explanation-2: -Conditions that arise from non-disjunction events include: Patau’s Syndrome (trisomy 13) Edwards Syndrome (trisomy 18) Down Syndrome (trisomy 21)
Detailed explanation-3: -Nondisjunction occurs when chromosomes fail to segregate during meiosis; when this happens, gametes with an abnormal number of chromosomes are produced. The clinical significance is high: nondisjunction is the leading cause of pregnancy loss and birth defects.
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