HEREDITY
NONDISJUNCTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Trisomy 16; A condition caused when a zygote receives 3 copies of chromosome 16
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Huntington’s Disease; A condition caused when a zygote receives a mutated dominant allele.
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Hemophilia; A condition caused when a zygote receives an X chromosome with a recessive sex-linked trait.
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Sickle Cell Anemia; A condition caused when a zygote receives to recessive alleles for hemoglobin.
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Detailed explanation-1: -Most cases of trisomy 16 result from nondisjunction in maternal meiosis I, which usually results in a first-trimester loss. If a trisomy 16 fetus is diagnosed on chorionic villus sampling or amniocentesis, then it is due to mosaicism in which one of the trisomic chromosomes is lost in mitotic cell division.
Detailed explanation-2: -ATR-16 syndrome is an extremely rare genetic disorder in which affected individuals have a large loss of genetic material (monosomy) on chromosome 16 in which several adjacent genes are lost.
Detailed explanation-3: -What is trisomy 16? Trisomy 16 is a type of chromosomal condition that happens when a fetus has an extra copy of chromosome 16-three copies instead of two. It occurs in around 1.5 percent of clinically recognized pregnancies (in other words, pregnancies where a woman knows she’s pregnant).
Detailed explanation-4: -Full trisomy 16 is incompatible with life and most of the time it results in miscarriage during the first trimester. This occurs when all of the cells in the body contain an extra copy of chromosome 16.