AP BIOLOGY

Detailed explanation-1: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-2: -Denaturation of enzymes causes bonds to be broken, structure to be disrupted and it stops functioning. This happens to enzymes when they are exposed to extreme, unsuitable conditions, for instance, high temperatures or extreme pH levels.

Detailed explanation-3: -Enzyme structures unfold (denature) when heated or exposed to chemical denaturants and this disruption to the structure typically causes a loss of activity.

Detailed explanation-4: -What denatures enzymes? There are two main causes for enzyme denaturation: temperature and pH. Enzymes function best at the optimal temperature of an organism.

Detailed explanation-5: -Enzymes are protein molecules that get denatured at high temperatures. High heat breaks hydrogen and ionic bonds leading to disruption in enzyme shape. The enzyme loses its activity and can no longer bind to the substrate.