AP BIOLOGY

LABORATORY REVIEW

CELL RESPIRATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
There is a toxic chemical absorbed that effects the pH of the mitochondrial matrix. What is likely to happen as a result of this situation?
A
Glycolysis will start to produce more ATP
B
The Krebs Cycle will continue to work with the ETC by relocating outside of the mitochondria
C
The ETC will continue to produce the same amount of ATP using NADH from glycolysis
D
The Krebs Cycle will not be able to produce high energy electron carriers to help power the ETC and aerobic respiration will fail
Explanation: 

Detailed explanation-1: -ANSWER A. ATP synthase acts as a proton channel in the inner mitochondrial membrane. If that channel were inhibited, protons would still be pumped out of the matrix by the ETC but would be unable to flow back in, causing the pH to rise.

Detailed explanation-2: -Low pH increases the concentration of base causing mitochondria to pump out H+ to the inter membrane space leading to ATP production.

Detailed explanation-3: -[link] After cyanide poisoning, the electron transport chain can no longer pump electrons into the intermembrane space. The pH of the intermembrane space would increase, the pH gradient would decrease, and ATP synthesis would stop.

Detailed explanation-4: -The preparatory reaction and the citric acid cycle are the reactions that take place in the matrix of the mitochondria. The preparatory reaction is the reaction in which pyruvate is converted to acetyl Coenzyme A. The citric acid cycle is a series of reactions through which acetyl Coenzyme A gets broken down.

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