AP BIOLOGY

LABORATORY REVIEW

CELL RESPIRATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the link reaction in aerobic respiration?
A
Pyruvate is carboxylated, acetyl reacts with coenzyme A, reducing NADH + H+
B
Pyruvate is decarboxylated, acetyl reacts with coenzyme A, forming NADH + H+
C
Pyruvate reacts with coenzyme A, forming NADH + H+
D
Pyruvate is decarboxylated, reacting with coenzyme A, reducing NADH + H+
Explanation: 

Detailed explanation-1: -The link reaction refers to the stage of respiration that “links” glycolysis to the Krebs (citric acid) cycle. In this stage, the products of glycolysis are converted into the reactants of the Krebs cycle. The final product of glycolysis is a pyruvate molecule.

Detailed explanation-2: -Anaerobic respiration (without oxygen) During glycolysis, glucose molecules (six-carbon molecules) are split into two pyruvates (three-carbon molecules) during a sequence of enzyme-controlled reactions. This is the same reaction as occurs in aerobic respiration.

Detailed explanation-3: -The link reaction takes place in the mitochondrial matrix and converts pyruvate into a molecule called acetyl coenzyme A (acetyl CoA). This stage does not produce any energy in the form of ATP but does produce reduced NAD and acetyl CoA.

Detailed explanation-4: -The link reaction occurs in the mitochondrial matrix. It dehydrogenates and decarboxylates the three-carbon pyruvate to produce the two-carbon acetyl CoA that can enter the Krebs Cycle.

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