AP BIOLOGY

LABORATORY REVIEW

CELL RESPIRATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why is it significant for NAD+ regeneration to happen in fermentation?
A
It replenishes the NAD+ needed to produce NADH in glycolysis
B
This will be shuttled to the chloroplast for photosynthetic use
C
NAD+ will be used to oxidize electrons in electron transport chain
D
It will react with the by-products to produce more ATP molecules
Explanation: 

Detailed explanation-1: -Correct! Fermentation allows continued glycolysis by regenerating NAD+ from NADH. NAD+ is limiting, and must be reformed to allow the continuation of the glycolytic degradation of glucose producing ATP.

Detailed explanation-2: -Answer and Explanation: The regeneration of NAD+ is a critical step of fermentation. In fact, you might even say it is the main purpose of fermentation. Fermentation occurs so that glycolysis can continue in the absence of oxygen since glycolysis requires NAD+ as an oxidizing agent.

Detailed explanation-3: -Nicotinamide adenine dinucleotide (NAD+) is an important molecule in glycolysis. It is a cofactor which regulates metabolism through its electron transport function in the redox reaction in glycolysis and the TCA cycle, In glycolysis, NAD+ reduces forming NADH and H+. If NAD+ is absent, glycolysis cannot continue.

Detailed explanation-4: -NAD+ can be regenerated in the cytoplasm from NADH through the conversion of pyruvate to lactate by the lactate dehydrogenase (LDH), thereby maintaining active aerobic glycolysis [5].

There is 1 question to complete.