AP BIOLOGY

Detailed explanation-1: -The induced fit theory of enzyme action was given by Daniel Koshland in 1958. According to this theory whenever a substrate binds to an enzyme it induces conformational change to the enzyme which strengthen its binding.

Detailed explanation-2: -The induced-fit model states a substrate binds to an active site and both change shape slightly, creating an ideal fit for catalysis. Enzymes promote chemical reactions by bringing substrates together in an optimal orientation, thus creating an ideal chemical environment for the reaction to occur.

Detailed explanation-3: -The induced-fit model was first proposed by Koshland in 1958 to explain the protein conformational changes in the binding process. This model suggests that an enzyme, when binding with its substrate, optimizes the interface through physical interactions to form the final complex structure.

Detailed explanation-4: -allosteric control …the basis of the so-called induced-fit theory, which states that the binding of a substrate or some other molecule to an enzyme causes a change in the shape of the enzyme so as to enhance or inhibit its activity.