AP BIOLOGY

Detailed explanation-1: -This means that the substrate cannot bind to the active site anymore. And this denatured enzyme can no longer catalyze enzyme-controlled reactions. When an enzyme denatures, this change in the shape of the active site is usually irreversible.

Detailed explanation-2: -If enzymes are denatured, they lose the shape of their active sites which means they cannot bind to their substrate, decreasing the rate of reaction.

Detailed explanation-3: -When an enzyme is denatured, these bonds holding the enzyme together are disrupted, leading to a loss of structure. Depending on the degree of denaturation, only the active site of the enzyme might be affected, reducing the ability for the enzyme to effectively bind to its substrate.

Detailed explanation-4: -The shape of the active site will change irreversibly, and it will no longer be able to bind to its substrate. The enzyme is said to be denatured, or we say that denaturation has occurred.

Detailed explanation-5: -Enzymes work consistently until they are dissolved, or become denatured. When enzymes denature, they are no longer active and cannot function. Extreme temperature and the wrong levels of pH–a measure of a substance’s acidity or alkalinity–can cause enzymes to become denatured.