LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A=C and G=T
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A pairs with T and G pairs with C
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A pairs with G and C pairs with T
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A pairs with C and G pairs with T
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Detailed explanation-1: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.
Detailed explanation-2: -In the Chargaff’s rules of base pairing are: Relation of A with T: The Pyrimidine Thymine (T) always pairs with the Purine Adenine (A) Relation of C with G: The Purine Guanine (G) always pair with the Pyrimidine Cytosine (C)
Detailed explanation-3: -Chargaff’s rule states that the amount of adenine (A) is equal to that of thymine (T) and the amount of guanine is equal to that of cytosine (C) in an organism.