LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Nuclear DNA
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Mitochondrial DNA
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Plasmid DNA
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Bacterial DNA
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Detailed explanation-1: -The D-loop occurs in the main non-coding area of the mitochondrial DNA molecule, a segment called the control region or D-loop region. Replication of the mitochondrial DNA can occur in two different ways, both starting in the D-loop region.
Detailed explanation-2: -The mitochondrial D-loop is a triple-stranded region found in the major non-coding region (NCR) of many mitochondrial genomes, and is formed by stable incorporation of a third, short DNA strand known as 7S DNA.
Detailed explanation-3: -Mitochondrial DNA replication is initiated at the origin for H-strand DNA replication (OH) and the origin for L-strand DNA replication (OL). During the initiation phase, replication is limited to the H strand only; no simultaneous L-strand synthesis occurs.
Detailed explanation-4: -The human mitochondrial genome is a genetically compact, circular, double-stranded DNA molecule of 16.5 kb, typically present at between 100 and 10, 000 copies per cell on a cell type-specific basis [12, 13].
Detailed explanation-5: -D-loop replication is a proposed process by which circular DNA like chloroplasts and mitochondria replicate their genetic material.