LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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rRNA
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mRNA
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ssDNA
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siRNA
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Detailed explanation-1: -Initiation and Unwinding During initiation, so-called initiator proteins bind to the replication origin, a base-pair sequence of nucleotides known as oriC. This binding triggers events that unwind the DNA double helix into two single-stranded DNA molecules.
Detailed explanation-2: -Every DNA/RNA base, A C G T and U, has only one possible pairing partner, so if the strand is open on one side (single strand), the opposite side can be inferred because only one sequence will match the existing strand’s base sequence. This property is usually called the Base Pairing property.
Detailed explanation-3: -The composition of ssRNA differs from that of ssDNA only by a single nucleotide (uracil in place of thymine). Based on their chemical similarity, uracil and thymine are expected to have similar stacking energies.
Detailed explanation-4: -ssDNA is a linear structure that has only one DNA strand. dsDNA has two DNA strands bound by hydrogen bonds in a helical fashion. It is found in a few viruses. It is a less stiff and stable structure.