LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Splicing and tailing
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Caping and tailing
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caping, tailing and splicing
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Splicing only
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Detailed explanation-1: -Eukaryotic mRNA primary transcripts undergo extensive processing, including splicing, capping and, polyadenylation.
Detailed explanation-2: -There is an addition of 7-methylguanylate at the 5’ end of the mRNA. This process is known as the capping of the mRNA. At the 3’ end of the mRNA, there is an addition of a chain of adenine nucleotides. This is known as the poly-A tail or the tailing mechanism.
Detailed explanation-3: -The pre-mRNA has to go through some modifications to become a mature mRNA molecule that can leave the nucleus and be translated. These include splicing, capping, and addition of a poly-A tail, all of which can potentially be regulated – sped up, slowed down, or altered to result in a different product.