LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A = G
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A + G = C + T
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A + T = G + G
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A = C
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Detailed explanation-1: -So, the correct option is ‘A+G=C+T’.
Detailed explanation-2: -Adenine (“A”) and Thymine (“T”) each have one donor and one acceptor, whereas Cytosine (“C”) has one donor and two acceptors, and Guanine (“G”) has one acceptor and two donors. The A nucleotides are always hydrogen bonded to T nucleotides, and C nucleotides are always hydrogen bonded to G nucleotides.
Detailed explanation-3: -Erwin Chargaff proposed the Chargaff’s rule. The rule played an essential role in discovering the double-helical structure of DNA. The rule states that in any double-stranded DNA, the ratios between Adenine and Thymine and Guanine and Cytosine are constant and equal.
Detailed explanation-4: -Final answer: Adenine-Thymine is the correct base pairing for DNA molecules.
Detailed explanation-5: -Replication relies on complementary base pairing, that is the principle explained by Chargaff’s rules: adenine (A) always bonds with thymine (T) and cytosine (C) always bonds with guanine (G).