LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Alexander Fleming
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Smith and Nathans
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Berg
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None
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Detailed explanation-1: -In 1978, the Nobel Prize in Physiology or Medicine was awarded jointly to Werner Arber, who predicted the existence of restriction enzymes, Hamilton Smith, who discovered the first Type II restriction enzyme, and Nathans, who demonstrated how to use the restriction enzymes to analyze viral DNA.
Detailed explanation-2: -So, the correct answer is ‘Smith and North’
Detailed explanation-3: -The term was coined by Lederberg and Messelson in 1964. These are found in bacterial cells, where they function as a part of a protective mechanism called restriction-modification system. Complete step by step answer: Hind II is the first restriction endonuclease isolated.
Detailed explanation-4: -Hamilton Smith verified this discovery. Using a purified restriction enzyme taken from a bacterium, in 1970, Smith was able to show that the restriction enzyme cleaves the DNA molecule in the middle of a symmetrical sequence of nucleotides.
Detailed explanation-5: -Werner Arber, Dan Nathans and Hamilton Smith for the discovery of “restriction enzymes and their application to problems of molecular genetics”.