LABORATORY REVIEW
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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replication
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synthesis
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transcription
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translation
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Detailed explanation-1: -Transcription is the first step in gene expression. It involves copying a gene’s DNA sequence to make an RNA molecule.
Detailed explanation-2: -During transcription, a piece of DNA that codes for a specific gene is copied into messenger RNA (mRNA) in the nucleus of the cell. The mRNA then carries the genetic information from the DNA to the cytoplasm, where translation occurs.
Detailed explanation-3: -Like DNA replication, transcription proceeds in the 5’ to 3’ direction (ie the old polymer is read in the 3’ to 5’ direction and the new, complementary fragments are generated in the 5’ to 3’ direction). Transcription is divided into 3 stages: initiation, elongation and termination.
Detailed explanation-4: -At this point, RNA polymerase begins moving down the DNA template strand in the 3’ to 5’ direction, and as it does so, it strings together complementary nucleotides. By virtue of complementary base-pairing, this action creates a new strand of mRNA that is organized in the 5’ to 3’ direction.