LABORATORY REVIEW
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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promotion.
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elongation.
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initiation.
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splicing.
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Detailed explanation-1: -The first step in transcription is initiation, when the RNA pol binds to the DNA upstream (5′) of the gene at a specialized sequence called a promoter (Figure 2a). In bacteria, promoters are usually composed of three sequence elements, whereas in eukaryotes, there are as many as seven elements.
Detailed explanation-2: -Transcription has three stages: initiation, elongation, and termination.
Detailed explanation-3: -The major steps of transcription are initiation, promoter clearance, elongation, and termination.
Detailed explanation-4: -Key points: Transcription begins when RNA polymerase binds to a promoter sequence near the beginning of a gene (directly or through helper proteins). RNA polymerase uses one of the DNA strands (the template strand) as a template to make a new, complementary RNA molecule.