LABORATORY REVIEW
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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leading strand
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lagging strand
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parallel strand
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antiparallel strand
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Detailed explanation-1: -The strand that runs in the 5’ to 3’ direction in the replication fork is referred to as the leading strand. The strand is replicated discontinuously. The strand is replicated continuously. Short stretches called okazaki fragments are formed during replication.
Detailed explanation-2: -Leading and lagging strands One new strand, the leading strand, runs 5’ to 3’ towards the fork and is made continuously. The other, the lagging strand, runs 5’ to 3’ away from the fork and is made in small pieces called Okazaki fragments.
Detailed explanation-3: -The leading strand is a single DNA strand that, during DNA replication, is replicated in the 3’ – 5’ direction (same direction as the replication fork). DNA is added to the leading strand continuously, one complementary base at a time.
Detailed explanation-4: -When replication begins, the two parent DNA strands are separated. One of these is called the leading strand, and it runs in the 3’ to 5’ direction and is replicated continuously because DNA polymerase works antiparallel, building in the 5’ to 3’ direction.
Detailed explanation-5: -This continuously synthesized strand is known as the leading strand. Because DNA polymerase can only synthesize DNA in a 5′ to 3′ direction, the other new strand is put together in short pieces called Okazaki fragments.