LABORATORY REVIEW
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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template antisense
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coding strand
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sense strand
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RNA strand
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Detailed explanation-1: -Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for producing messenger RNA (mRNA), which directs the synthesis of a protein.
Detailed explanation-2: -The template strand acts as a base for mRNA transcription. It is also known as sense strand (plus strand) or coding strand. It is the antisense strand (minus strand) or a non-coding strand. They do not take part in the transcription process.
Detailed explanation-3: -The DNA strand that serves as a template for mRNA synthesis is called as anticoding strand or antisense strand or noncoding strand. The other strand is called coding strand or sense strand as its base sequence is same as that of newly synthesized mRNA.
Detailed explanation-4: -Strictly speaking, only the mRNA makes “sense” with the genetic code, as the translated protein peptide sequence can be directly inferred from this strand. The “antisense” strand of DNA is complementary to the “sense” strand and is the actual template for mRNA synthesis.
Detailed explanation-5: -Antisense: In molecular biology, the strand complementary to a coding sequence of a nucleic acid. Antisense DNA is the non-coding strand complementary to the coding strand in double-stranded DNA. The antisense strand serves as the template for messenger RNA (mRNA) synthesis.