AP BIOLOGY

LABORATORY REVIEW

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
WHICH MUTATION WOULD MOST LIKELY HAVE THE MOST HARMFUL EFFECT?
A
A single addition
B
a single substitution
C
insertion of a triplet
D
deletion of a triplet
Explanation: 

Detailed explanation-1: -So, the correct option is ‘A single base insertion near the start of the coding sequence’.

Detailed explanation-2: -Answer and Explanation: The type of mutation that is likely to have the greatest effect on a protein is B. Nonsense mutation. This is because a nonsense mutation creates a premature stop codon, leading to an incomplete formation of a protein, severely affecting protein structure and function.

Detailed explanation-3: -The answer is A, frameshift mutation. Therefore, multiple amino acids in a protein change.

Detailed explanation-4: -So, the correct option is ‘A missense substitution’

Detailed explanation-5: -A point mutation-the change of a single nitrogen base in a DNA sequence-is usually the least harmful type of DNA mutation.

There is 1 question to complete.