AP BIOLOGY

THE CELL

CELL COMMUNICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cancer cells make and respond to their own growth signals, which leads to uncontrolled continuation of the cell cycle. This is an example of
A
endocrine signaling.
B
paracrine signaling.
C
autocrine signaling.
D
juxtacrine signaling.
Explanation: 

Detailed explanation-1: -Autocrine signaling also plays a vital role in cellular homeostasis. For example, progesterone has been found to act as an autocrine signal in breast cancer. Cell signaling is the form of communication between cells. Cells communicate with each other through several cell signaling pathways.

Detailed explanation-2: -This is called metastasis. Cancer is a disease caused when cells divide uncontrollably and spread into surrounding tissues. Cancer is caused by changes to DNA. Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes.

Detailed explanation-3: -Wnt/-catenin signaling Dysregulated Wnt signaling is linked to numerous cancers including; leukemia, melanoma, breast and gastrointestinal cancers.

Detailed explanation-4: -Autocrine stimulation refers to positive autocrine secretion, which functions to stimulate cell growth. Many of the positive autocrine loops have been demonstrated in human colorectal carcinoma (CRC), which are considered to play an important role in the initiation and progression of the cancer.

There is 1 question to complete.