THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Cancercells replicate chromosomes multiple times per cell cycle
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Cancercells are no longer anchorage dependent
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Cellcycle checkpoints are not in place to stop cells with chromosome abnormalities
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Cellswith abnormal chromosomes have increased metabolism
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Detailed explanation-1: -Two prominent features of cancer cells are abnormal numbers of chromosomes (aneuploidy) and large-scale structural rearrangements of chromosomes. These chromosome aberrations are caused by genomic instabilities inherent to most cancers.
Detailed explanation-2: -Cells from advanced malignant tumors often have very abnormal chromosomes as well as an abnormal number of chromosomes. What might explain the association between malignant tumors and chromosomal abnormalities? Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities.
Detailed explanation-3: -A common characteristic of all malignant tumors is that they promote tumor cell proliferation and affect the immune system, both of which are closely associated with chromosome abnormalities.
Detailed explanation-4: -Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes. A DNA change can cause genes involved in normal cell growth to become oncogenes. Unlike normal genes, oncogenes cannot be turned off, so they cause uncontrolled cell growth.