THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Chromosomally abnormal cells can still go through cell cycle checkpoints.
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Transformation introduces new chromosomes into cells.
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Detailed explanation-1: -Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance called aneuploidy, which can skew the activity of hundreds or thousands of genes.
Detailed explanation-2: -Cells from advanced malignant tumors often have very abnormal chromosomes as well as an abnormal number of chromosomes. What might explain the association between malignant tumors and chromosomal abnormalities? Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities.
Detailed explanation-3: -Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes.
Detailed explanation-4: -A common characteristic of all malignant tumors is that they promote tumor cell proliferation and affect the immune system, both of which are closely associated with chromosome abnormalities.