AP BIOLOGY

Detailed explanation-1: -Cyclic adenosine monophosphate (cAMP) was the original “second messenger” to be discovered. Its formation is promoted by adenylyl cyclase activation after ligation of G protein–coupled receptors by ligands including hormones, autocoids, prostaglandins, and pharmacologic agents.

Detailed explanation-2: -Cyclic AMP (cAMP) is an intracellular second messenger to a wide variety of hormones and neurotransmitters. In T cells, elevated cAMP levels antagonize T cell activation by inhibiting T cell proliferation and by suppressing the production of IL-2 and IFN-.

Detailed explanation-3: -Adenosine 3′, 5′-cyclic monophosphate (cAMP) is a nucleotide that acts as a key second messenger in numerous signal transduction pathways. cAMP regulates various cellular functions, including cell growth and differentiation, gene transcription and protein expression.

Detailed explanation-4: -Cyclic AMP (cAMP) Some of the hormones that achieve their effects through cAMP as a second messenger: adrenaline. glucagon. luteinizing hormone (LH)