AP BIOLOGY

Detailed explanation-1: -At the spindle checkpoint, the cell checks for: Chromosome attachment to spindle at the metaphase plate.

Detailed explanation-2: -During metaphase, the kinetochore microtubules pull the sister chromatids back and forth until they align along the equator of the cell, called the equatorial plane. There is an important checkpoint in the middle of mitosis, called the metaphase checkpoint, during which the cell ensures that it is ready to divide.

Detailed explanation-3: -The M checkpoint occurs near the end of the metaphase stage of mitosis. The M checkpoint is also known as the spindle checkpoint because it determines whether all the sister chromatids are correctly attached to the spindle microtubules.

Detailed explanation-4: -The M phase checkpoint ensures that all chromosomes are attached to the mitotic spindle.

Detailed explanation-5: -DNA synthesis Checkpoint: The S checkpoint determines if the DNA has been replicated properly. The mitosis checkpoint: This checkpoint ensures that all the chromosomes are properly aligned before the cell is allowed to divide.