THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Production of the ligand molecule.
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Reception of the signal.
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Transduction of the signal.
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Production of response to signal.
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Detailed explanation-1: -The main physiological functions of G-proteins are to relay the signals from GPCRs which function as GEFs for G-proteins. Binding with exogenous or endogenous agonists induces GPCRs into an active conformational state which, in turn, influences intracellular binding of G-proteins or arrestin proteins [23, 24].
Detailed explanation-2: -G proteins are a family of receptor proteins that are involved in transmitting signals from outside a cell to inside a cell. When a signaling molecule binds to a G protein, the G protein is activated. The G protein then activates an enzyme that produces a second messenger called cAMP.
Detailed explanation-3: -G protein coupled receptors (GPCRs) are integral membrane proteins that are used by cells to convert extracellular signals into intracellular responses, including responses to hormones, neurotransmitters, as well as responses to vision, olfaction and taste signals.
Detailed explanation-4: -GPCRs are a large family of cell surface receptors that respond to a variety of external signals. Binding of a signaling molecule to a GPCR results in G protein activation, which in turn triggers the production of any number of second messengers.