AP BIOLOGY

Detailed explanation-1: -Glucagon triggers your liver to convert stored glucose (glycogen) into a usable form and then release it into your bloodstream. This process is called glycogenolysis. Glucagon can also prevent your liver from taking in and storing glucose so that more glucose stays in your blood.

Detailed explanation-2: -When blood glucose levels fall too low (low blood glucose), the pancreas pumps out more glucagon. This hormone helps blood glucose rise back up in multiple ways: It causes the liver to convert stored glucose into a usable form and then release it into the bloodstream. (A process called glycogenolysis.)

Detailed explanation-3: -Activation of the glucagon receptor results in adenylate cyclase activation and cAMP formation. The increase in intracellular cAMP levels activates protein kinase A (PKA), which phosphorylates the transcription factor cAMP-response-element-binding (CREB) protein.

Detailed explanation-4: -The glucagon signaling pathway activates hepatocyte phosphorylase and accelerates glycogenolysis through the cAMP-PK system. The gluconeogenesis is enhanced as hormones accelerate the entry of amino acids into the liver cells and activate the enzyme system involved in the gluconeogenesis process.

Detailed explanation-5: -What is Glucagon Signaling Pathway? The glucagon signaling pathway is a process of a series of elevated blood glucose enzymatic reactions triggered by the binding of glucagon that produced by pancreatic islets alpha cells to the glucagon receptor on the surface of liver cells.