THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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nuclearenvelope breakdown
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elongationof microtubules
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shortening of microtubules
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formationof a cleavage furrow
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Detailed explanation-1: -Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends. J Cell Biol (1987) 104 (1): 9–18. During the movement of chromosomes in anaphase, microtubules that extend between the kinetochores and the poles shorten.
Detailed explanation-2: -It has been postulated that the observed movement of the chromatids toward the pole in anaphase may be the result of shortening of the microtubules via depolymerization at the kinetochore end.
Detailed explanation-3: -16 Vincristine is a chemotherapy drug used to treat cancer. It prevents spindle formation during mitosis.
Detailed explanation-4: -Colchicines prevent spindle formation during mitotic metaphase. Thus, it prevents the separation of chromosomes during anaphase stage.