AP BIOLOGY

THE CELL

CELL COMMUNICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times.The research team used the setup to study the incorporation of labeled nucleotides into a culture of lymphocytes and found that the lymphocytes incorporated the labeled nucleotide at a significantly higher level after a pathogen was introduced into the culture. They concluded that
A
the presence of the pathogen made the experiment too contaminated to trust the results.
B
infection causes lymphocytes to divide more rapidly.
C
infection causes lymphocyte cultures to skip some parts of the cell cycle.
Explanation: 

Detailed explanation-1: -Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times.

Detailed explanation-2: -During interphase, the cell grows and makes a copy of its DNA. During the mitotic (M) phase, the cell separates its DNA into two sets and divides its cytoplasm, forming two new cells.

Detailed explanation-3: -In addition to driving the events of M phase, MPF also triggers its own destruction by activating the anaphase-promoting complex/cyclosome (APC/C), a protein complex that causes M cyclins to be destroyed starting in anaphase.

Detailed explanation-4: -Four stages of a typical cell cycle This lag period is called Gap 1 (G1), and ends with the onset of the DNA synthesis (S) phase, during which each chromosome is replicated. Following replication, there may be another lag, called Gap 2 (G2), before mitosis (M).

Detailed explanation-5: -Before the cell undergoes mitosis, the cell must make two copies of its DNA so that each daughter cell has a complete copy of the genetic material. At the onset of mitosis the nuclear envelope dissolves, and each chromosome lines up with its copy.

There is 1 question to complete.