AP BIOLOGY

Detailed explanation-1: -Ligand-Gated Ion Channels Binding of ligand to the exofacial surface of the receptor generates a conformational change that results in the opening of a pore, allowing specific ions to travel through the channel across the plasma membrane (Fig.

Detailed explanation-2: -Ligand-gated ion channels bind neurotransmitters and open in response to ligand binding. These channels control synaptic transmission between two neurons or between a neuron and a muscle.

Detailed explanation-3: -Ligand-gated ion channels are oligomeric protein assemblies that convert a chemical signal into an ion flux through the post-synaptic membrane, and are involved in basic brain functions such as attention, learning, and memory (Ashcroft, 2006).

Detailed explanation-4: -Ligand-gated ion channels open when a chemical ligand such as a neurotransmitter binds to the protein. Voltage channels open and close in response to changes in membrane potential.