THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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the synthesis of mRNA
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the activation of an inactive enzyme
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alteration of the cytoskeleton
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a change in the chemical composition of the cytosolic environment
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the activation of a metabolic pathway
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Detailed explanation-1: -Transcription termination factor (TTF-I) is an RNA polymerase-1-mediated transcription terminator (1). It binds to a consensus terminator element composed of a so-called ‘Sal box’ 11-base pair motif (GGGTCGACCAG), which can be repeated up to 10 times downstream of the 3′ end of the pre-rRNA sequence (2).
Detailed explanation-2: -To date, the roles of phosphoinositide 3-kinase (PI3K)/AKT and the mitogen-activated protein kinase (MAPK) pathways in the regulation of translation are among the best understood. Both pathways engage the mechanistic target of rapamycin (mTOR) to regulate a variety of components of the translational machinery.
Detailed explanation-3: -mRNA is created during transcription. During the transcription process, a single strand of DNA is decoded by RNA polymerase, and mRNA is synthesized. Physically, mRNA is a strand of nucleotides known as ribonucleic acid, and is single-stranded.
Detailed explanation-4: -The synthesis of mRNA from DNA occurs in several stages: initiation, elongation, editing (processing), and termination. Initiation of transcription (the synthesis of mRNA) occurs when factors that serve to stabilize nuclear DNA are perturbed. Perturbation signals pass in to the nucleus and stimulate transcription.