AP BIOLOGY

Detailed explanation-1: -The segregation of the replicated chromosomes is brought about by a complex cytoskeletal machine with many moving parts-the mitotic spindle. It is constructed from microtubules and their associated proteins, which both pull the daughter chromosomes toward the poles of the spindle and move the poles apart.

Detailed explanation-2: -Anaphase. The separation of sister chromatids marks the commencement of anaphase followed by the movement of chromosomes toward the spindle poles.

Detailed explanation-3: -The chromosomes are separated by a structure called the mitotic spindle. The mitotic spindle is made of many long proteins called microtubules, which are attached to a chromosome at one end and to the pole of a cell at the other end. The sister chromatids are separated simultaneously at their centromeres.

Detailed explanation-4: -A central feature of mitosis is segregation of sister chromatids to opposite poles during anaphase.

Detailed explanation-5: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell.