AP BIOLOGY

Detailed explanation-1: -Juxtacrine signaling occurs between neighboring cells that are in physical contact with each other. In this case, the signaling molecule is not free, but is instead bound to the membrane of the cell. It may then interact with a receptor on the membrane of an adjacent cell.

Detailed explanation-2: -In biology, juxtacrine signalling (or contact-dependent signalling) is a type of cell–cell or cell–extracellular matrix signalling in multicellular organisms that requires close contact. In this type of signalling, a ligand on one surface binds to a receptor on another adjacent surface.

Detailed explanation-3: -Paracrine signaling involves the secretion of specific signaling factors by one cell which are perceived by corresponding receptors on another cell in the vicinity, triggering a response in it9, 10, whereas juxtacrine signaling requires direct contact between cellular components of the two cells involved11, 12.

Detailed explanation-4: -In juxtacrine interactions, proteins from the inducing cell interact with receptor proteins of adjacent responding cells. The inducer does not diffuse from the cell producing it. There are three types of juxtacrine interactions. In the first type, a protein on one cell binds to its receptor on the adjacent cell.

Detailed explanation-5: -Cells typically communicate using chemical signals. These chemical signals, which are proteins or other molecules produced by a sending cell, are often secreted from the cell and released into the extracellular space. There, they can float – like messages in a bottle – over to neighboring cells.