AP BIOLOGY

THE CELL

CELL COMMUNICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What would prevent a ligand from binding to its receptor?
A
Change in the cytoskeleton attachment of the transmembrane protein
B
Presence of a large amount of precursor to the ligand
C
Increase in the ratio of saturated to unsaturated cell membrane lipids
D
A mutation in the receptor gene that changes an amino acid at the binding site
Explanation: 

Detailed explanation-1: -What property prevents the ligands of cell-surface receptors from entering the cell? The molecules bind to the extracellular domain. The molecules are hydrophilic and cannot penetrate the hydrophobic interior of the plasma membrane.

Detailed explanation-2: -Ion Channel Receptors When a ligand binds an ion channel receptor, a channel through the plasma membrane opens that allows specific ions to pass through. This process requires a specialized membrane-spanning region of the receptor.

Detailed explanation-3: -Ligand binding to a receptor protein alters the conformation by affecting the three-dimensional shape orientation. The conformation of a receptor protein composes the functional state. Ligands include substrates, inhibitors, activators, signaling lipids, and neurotransmitters.

Detailed explanation-4: -When a ligand is released, what prevents all of the cells in the body from being affected? Ligands are specific to their receptors, so the inactive relay proteins and secondary messengers that are released in the cell to initiate a response are specific to that ligand.

There is 1 question to complete.