THE CELL
CELL COMMUNICATION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
cAMP
|
|
|
RTK’s
|
|
|
Ca2+
|
|
|
sodium
|
Detailed explanation-1: -DAG and IP3 are second messengers that can act independently or in unison. DAG activates protein kinase C and IP3 binds to a receptor on the endoplasmic reticulum to release calcium from intracellular stores.
Detailed explanation-2: -Calcium ion (Ca(2+)) plays an important role in stimulus-response reactions of cells as a second messenger.
Detailed explanation-3: -Cyclic AMP (cAMP) and calcium (Ca2+) are arguably the prototypical second messengers that control cellular homeostasis. Whereas, for instance, nitric oxide and cyclic GMP may serve essential functions in a number of physiological situations, cAMP and Ca2+ are the only truly ubiquitous second messengers.
Detailed explanation-4: -There are 3 major classes of second messengers: cyclic nucleotides (e.g., cAMP and cGMP) inositol trisphosphate (IP3) and diacylglycerol (DAG)
Detailed explanation-5: -It is well known that calcium is an important second messenger in the cardiovascular system. However, recent studies suggest that, in addition to its many functions as an intracellular messenger, Ca2+ may also be an extracellular first messenger through the calcium-sensing receptor (CaR).