AP BIOLOGY

Detailed explanation-1: -Nondisjunction would occur at the spindle checkpoint, and so the cell is supposed to be stopped and the error corrected there.

Detailed explanation-2: -The M checkpoint determines whether all the sister chromatids are correctly attached to the spindle microtubules before the cell enters the irreversible anaphase stage.

Detailed explanation-3: -M checkpoint – nuclear division setup check It is also called the spindle checkpoint because the cell examines whether all sister chromatids are correctly attached to the spindle microtubules that separate them. If not, the cell pauses mitosis until all sister chromatids have been attached in the right way.

Detailed explanation-4: -If a checkpoint fails or if a cell suffers physical damage to chromosomes during cell division, or if it suffers a debilitating somatic mutation in a prior S phase, it may selfdestruct in response to a consequent biochemical anomaly. This is another example of apoptosis.